Through a series of sequential analyses, retrospective database exploration looking for linkages and associations between the use of processed electroencephalogram (EEG) and/or cerebral saturation monitoring and patient outcomes post-cardiothoracic surgery will be explored.
The purpose of this study is to mine the Premier Healthcare Database to: 1. define the incidence of post-operative cognitive complications, acute kidney injury and stroke after specific cardiac surgical procedures (defined as: coronary artery bypass graft \[CABG\], Aortic Valve Replacement, Mitral valve repair, Mitral valve replacement, thoracic aortic operation, combined CABG and Valve replacement or repair ; and 2. Determine the incremental increase in the length of hospitalization and cost of hospitalization among cardiac surgical patients who suffer postoperative cognitive complications, acute kidney injury and stroke; and 3. Determine the effectiveness of intraoperative neuromonitoring with cerebral saturation and/or processed electroencephalogram (EEG) monitoring on the incidence of post-operative cognitive complications, acute kidney injury and stroke as a consequence of specific cardiac surgery procedures. The Premier Healthcare Database is a privately owned database that represents approximately 1/5th of all United States hospitalizations annually. It includes all International Classification of Diseases-9th Revision (ICD-9) and International Classification of Diseases-Clinical Modification (ICD-9-CM) diagnosis and procedure codes recorded by the hospital, as well as a limited set of Current Procedural Terminology (CPT)-4 codes. Within the database, discharge-level data include information on patient and provider characteristics, diagnoses and procedures, hospital resource utilization, and charges/cost data for all entries, including pharmacy charges.
Study Type
OBSERVATIONAL
Enrollment
250,000
Vanderbilt University School of Medicine
Nashville, Tennessee, United States
Delirium: Incidence of post-operative cognitive complications identified by ICD-9 diagnosis code
Incidence of post-operative cognitive complications identified by International Classification of Disease (ICD-9) diagnosis code
Time frame: 5 years
Acute Kidney Injury: Incidence of acute kidney injury identified by ICD-9 diagnosis code
Incidence of acute kidney injury identified by ICD-9 diagnosis code
Time frame: 5 years
Stroke: Incidence of stroke identified by ICD-9 diagnosis code
Incidence of stroke identified by ICD-9 diagnosis code
Time frame: 5 years
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