Ivabradine to Improve Endothelial Function in Patients With Coronary Artery Disease

Inclusion Criteria: * history of stable coronary disease * complete coronary revascularization with PCI at least 1 month prior to recruitment * sinus rhythm * absence of anginal symptoms Exclusion Criteria: * resting heart rate \<60 beats per minute * severe reduction of left ventricle ejection fraction (\<40%) * coronary artery by-pass surgery * myocardial infarction, stroke or cerebral transient ischemic attack within the previous 6 months * implanted pacemaker, cardioverter, or defibrillator * sick sinus syndrome * sinoatrial block * congenital long QT * complete atrioventricular block