Evaluating the Efficacy of a Novel Oral Supplement in Tackling Malnutrition in the Elderly

Inclusion Criteria: * age 65+ * at risk of malnutrition/ malnourished Exclusion Criteria: * • Mental status that is incompatible with the proper conduct of the study * Illness of such severity that life expectancy is considered to be less than 12 months * Use of diabetes medication (e.g. insulin, methformin) * Use of an oral nutritional supplement in the previous three months * Participating in any regular exercise training program (≥2h/w) * Renal insufficiency (eGFR \<30 mL/min/1.73 m2) * Unstable organ failure or organ failure necessitating a special diet * Chronic corticosteroids use * Recent (previous 2 months) use of antibiotics * Recent (previous 3 months) change in habitual medication use (e.g statins and thyroxin) * Recent blood donation (\<1 month prior to Day 01 of the study) * Not willing or afraid to give blood during the study * Allergic or sensitive for milk proteins * Reported vegan or macrobiotic life-style * Drug and/or alcohol abuse (current consumption of more than 21 alcoholic drinks per week) * Individual unable to give informed consent * Current participation in other research from the Division of Human Nutrition * Not having a general practitioner * Personnel of Wageningen University, department of Human Nutrition, their partner and their first and second degree relatives