Prophylactic Tamsulosin Use for Prevention of Post-Operative Urinary Retention

University of Rochester5 enrolled

Overview

This randomized open-label study will be comprised of 2 cohorts: one control group and one treatment group. The trial will be conducted as an open label randomized trial to evaluate the efficacy of tamsulosin in the prevention of post-operative urinary retention. The study will include pre- and post-surgical evaluations of patients including symptoms of urinary retention and any adverse effects contributable to the study medication.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

PREVENTION

Masking

NONE

Enrollment

Conditions

Post-Operative Urinary Retention

Interventions

TamsulosinDRUG

Tamsulosin may have prophylactic properties against post-operative urinary retention

EducationOTHER

Education about signs and symptoms of urinary retention

Eligibility

Sex: MALEMin age: 40 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Any male age 40 or older * Scheduled to undergo one of the planned surgeries (thoracic, general, or urologic) * Ability to give informed consent Exclusion Criteria: * Current use of alpha blocker * Current use of a strong CYP 3A4 inhibitors * Any allergy to tamsulosin, alpha-blocker medication class, or anaphylaxis allergy to sulfate containing medications * Patients with any upcoming surgery for cataracts * Currently enrolled in a clinical trial * Inability to give informed consent

Locations (1)

University of Rochester

Rochester, New York, United States

Outcomes

Primary Outcomes

Number of Participants With Post-operative Urinary Retention

Time frame: 5 days

Data from ClinicalTrials.gov

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