Mapping Human Muscle Satellite Cell Fate By Real-Time Imaging

Purdue University7 enrolled

Overview

The aim of this study is to obtain human muscle samples for cell culturing to analyze muscle cell development in real-time to uncover factors that influence growth.

Study Type

INTERVENTIONAL

Allocation

Purpose

OTHER

Masking

NONE

Enrollment

Conditions

Flaccid Muscle Tone

Interventions

muscle biopsyPROCEDURE

a muscle sample will be taken from the mid-thigh (Vastus Lateralis) and analyzed

Eligibility

Sex: MALEMin age: 20 YearsMax age: 29 YearsHealthy volunteers:

Medical Language ↔ Plain English

-Inclusion Criteria: * men 20-29 yrs * BMI between 20 and 34.9 * Fasting Glucose \<110 mg/dL * Blood Pressure \<160/100mm Hg * Non-Diabetic * LDL-Cholesterol \<160mg/dL * Triacylglycerol \<400 mg/dL * Makers of kidney, liver, and heart functions within 10% of clinical normalcy * \<1.5hr /wk of habitual aerobic exercise training and no resistance exercise training in the past 6 months Exclusion Criteria: * men \<20or\>29 yrs * BMI between \<20 and \>34.9 * Fasting Glucose \>110 mg/dL * Blood Pressure \>160/100mm Hg * Non-Diabetic * LDL-Cholesterol \>160mg/dL * Triacylglycerol \>400 mg/dL * Pre-existing kidney or liver conditions --\>1.5hr /wk of habitual aerobic exercise training and no resistance exercise training in the past 6 months * Currently taking prescribed blood thinners

Locations (1)

Purdue University - Stone Hall 700 W State St

West Lafayette, Indiana, United States

Outcomes

Primary Outcomes

Mapping Human Muscle Satellite Cell Fate By Real-Time Imaging

this study is to obtain human muscle samples for cell culturing which will be exposed to a novel real-time imaging technique in order to elucidate factors that influence muscle satellite cell growth.

Time frame: <10 hrs

Data from ClinicalTrials.gov

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