Mobile Health Fitness Program for Adolescent and Young Adult Childhood Cancer Survivors

Rutgers, The State University of New Jersey49 enrolled

Overview

This clinical trial studies a mobile health fitness program for adolescent and young adult childhood cancer survivors. Adolescent and young adult childhood cancer survivors are at risk to have negative late effects from treatment and to develop chronic health conditions. A sedentary lifestyle may increase the risk of cardiovascular disease, osteoporosis, and early mortality. Physical activity reduces the risk for cardiovascular disease and early mortality, improves cardiorespiratory fitness, muscular fitness, bone health, and body composition, and it is also positively associated with quality of life. Programs and technologies that promote physical activity are important because health behaviors adopted by adolescent and young adult childhood cancer survivors are likely to continue into adulthood. A mobile health fitness application may motivate adolescent and young adult childhood cancer survivors to engage and maintain physical activity.

PRIMARY OBJECTIVES: I. Evaluate the feasibility of the technology-enhanced (electronic accelerometer + app + 8 weekly group sessions) fitness program in a pilot randomized clinical trial. SECONDARY OBJECTIVES: I. Determine the effectiveness of the technology-enhanced fitness program on participants' cardiorespiratory fitness and muscular fitness. II. Examine the effects of the program on secondary outcomes of health related quality of life (HRQOL) and fatigue. OUTLINE: Participants are randomized to 1 of 2 arms. ARM I (Intervention): Participants attend 8 group meetings weekly, wear an electronic accelerometer, engage in private social support messaging within the app and Facebook private groups, and then use the mobile app for 4 weeks without in-person groups. ARM II (WAITLIST CONTROL \[WLC\]): After the 6 month assessment, participants receive the FitSurvivor intervention as in arm I.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

SUPPORTIVE_CARE

Masking

NONE

Enrollment

Eligibility

Sex: ALLMin age: 13 YearsMax age: 25 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Any diagnosis of cancer prior to age 21 * Off treatment for at least 6 months * For patients \< 18 years, parents must give informed consent and patient must give assent; patients \>= 18 must give informed consent Exclusion Criteria: * Any medical contraindication to exercise according to a physician or physician's designee * Non-English speaking * Current physical activity level exceeding Centers for Disease Control and Prevention (CDC) guidelines for activity (60 min of moderate-vigorous exercise/day for 5+ days/week (wk) including 3+ days of vigorous intensity activities and muscle-strengthening exercises on 3+ days/wk and bone strengthening exercises on 3+ days/wk for children \< 18 and 150 min of moderate vigorous exercise or 75 min of vigorous exercise/wk and 2+ days of muscle strengthening activities for adults \>= 18); the CDC guidelines are used to determine exercise prescription in our intervention; individuals already exceeding the guidelines would be unlikely to benefit from participating * Significant developmental delay per patient, parent, or physician report * Pregnant (per patient report); if participant becomes pregnant during the course of the study, she will be removed from further participation

Outcomes

Primary Outcomes

Feasibility of the Technology-enhanced Fitness Program

Feasibility will be evaluated by the number of participants who enroll and complete baseline assessment for the randomized trial. In total, 354 participants were mailed letters; 68 were contacted/screened, of which 56 were eligible and 49 enrolled (88% of those screened eligible, 14% of total potentially eligible pool).

Time frame: Baseline