Does Preoperative Administration of Oral Doxycycline Decrease the Colonization Rate of Propionibacterium Acnes in the Dermis of the Shoulder?

Rothman Institute Orthopaedics

Overview

The purpose of this study is to evaluate the ability of oral doxycycline to decrease the colonization of Propionibacterium acnes in the dermis of the shoulder.

Study Type

INTERVENTIONAL

Purpose

PREVENTION

Conditions

Propionibacterium

Interventions

DoxycyclineDRUG

Eligibility

Medical Language ↔ Plain English

Inclusion Criteria: -All male patients (\>18 years of age) undergoing shoulder arthroscopy Exclusion Criteria: * Female patients * patients with active acne * patients who have taken antibiotics in the past month * doxycycline allergy * benzoyl peroxide allergy * clindamycin allergy * patients with psoriatic/eczematous or other lesions on the shoulder girdle.

Outcomes

Primary Outcomes

Quantification of P acnes grown from anaerobic or aerobic culture

Time frame: within 14 days of surgery

Data from ClinicalTrials.gov

This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.