TEG (Thromboelastography) Based Versus Conventional Coagulation Parameters Based Correction of Coagulopathy in Non Variceal Bleed.

Institute of Liver and Biliary Sciences, India96 enrolled

Overview

All patients with non variceal bleed who are admitted under the Department of Hepatology at Institute of Liver and Biliary Sciences, who meet the inclusion criteria and who provide informed consent.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

DIAGNOSTIC

Masking

NONE

Enrollment

Conditions

Non Variceal Bleed

Interventions

Fresh Frozen PlasmaBIOLOGICAL

Platelets ConcentrateBIOLOGICAL

Cryo PrecitipitateBIOLOGICAL

Eligibility

Sex: ALLMin age: 18 YearsMax age: 80 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Age more than 18 * All patient with Non Variceal bleed (INR\>1.8 and platelets\<50000) * Hist logical or imaging proven liver cirrhosis. Exclusion Criteria: 1. Variceal Bleed, 2. Pregnancy., 3. Patients on anticoagulation 4. Patients who refused to participate in the study 5. Post EVL ulcer bleed

Locations (2)

Institute of Liver & Biliary Sciences

New Delhi, National Capital Territory of Delhi, India

Institute of liver and Biliary Sciences

New Delhi, National Capital Territory of Delhi, India

Outcomes

Primary Outcomes

Amount of FFP (Fresh Frozen Plasma) transfusion in both groups

Time frame: 42 days

Secondary Outcomes

Number of patients with bleed in both groups

Time frame: 5 days

Incidence of TRALI (Transfusion associated lung injury) and TACO ( Transfusion associated circulatory overload) in both the groups.

Time frame: 42 days

Early mortality ( <6 weeks) and late mortality (> 6 weeks) in both the groups.

Time frame: 42 days

Amount of blood products (Platelet and cryo and Red Blood Cells)transfused in both the groups.

Time frame: 42 days

Data from ClinicalTrials.gov

This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.