Three Different Oral Hygiene Regimes on Three Volatile Sulfur Compounds

Tokyo Medical and Dental University30 enrolled

Overview

The purpose of the study is to evaluate the effect of various oral hygiene regimes on three volatile sulfur compounds.

Thirty male monk volunteers who matched with the including criteria were divided randomly into two groups. Both groups were practiced to brush their teeth with scrubbing method for one week. Then, each group were instructed to do different additional protocol regimen- group A have to do mouth washing and tooth brushing and group B have to practice tongue cleaning addition to tooth brushing for three weeks. At the fifth week, both groups were instructed to practice tooth brushing, mouth washing and tongue cleaning. Three different volatile sulfur compounds were measured by oral chroma. Tongue characteristics, oral examination were checked as the outcomes of this study.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

PREVENTION

Masking

SINGLE

Enrollment

Conditions

Halitosis

Interventions

chlorine dioxideOTHER

First week, subjects were instructed to do regular tooth brushing. After that group A was requested to use chlorine dioxide mouthwash two time per days for three weeks in addition to tooth brushing and then, one week for combination of tooth brushing, tongue cleaning and mouth washing.

small toothbrush for tongue cleaningOTHER

First week, subjects were instructed to do regular tooth brushing. After that group B was requested to brush their tongue with small toothbrush two time per days for three weeks in addition to tooth brushing and then, one week for combination of tooth brushing, tongue cleaning and mouth washing.

Eligibility

Sex: MALEMin age: 18 YearsMax age: 30 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * Clinical diagnosis of oral malodor * No systemic diseases and no severe dental diseases * At least 20 functional teeth Exclusion Criteria: * Risky oral habit (smoking and betel quid chewing) * Current use of antibiotics or any drugs * Current use of any kind of mouthwash

Outcomes

Primary Outcomes

Three different volatile sulfur compounds

Investigator measured three different volatile sulfur compounds: hydrogen sulfide, methyl mercaptan, dimethyl sulfide concentrations (ng/10ml) by using Oral chroma.

Time frame: up to 5weeks

Secondary Outcomes

Oral Health examination

As oral examination, investigator examined present teeth, DMF-T (decayed, missing and filled teeth)

Time frame: up to 5weeks

Tongue coating characteristics

As tongue coating characteristics, investigator examined tongue coating score (by using winkle tongue coating index) at the baseline, one week later, four weeks later and five weeks later.

Time frame: up to 5weeks

Number of teeth with bleeding on probing

Time frame: up to 5weeks

Plaque index score

Time frame: up to 5weeks

Data from ClinicalTrials.gov

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