Quadratus Lumborum Block for Postoperative Analgesia After Colostomy Closure

Sun Yat-sen University50 enrolled

Overview

Patients undergoing abdominal procedures often require multimodal postoperative pain controls. Truncal blocks such as quadratus lumborum (QL) block may be used adjunctively as a part of it. The investigators hypothesized that the ultrasound-guided QL block with transmuscular approach can provide adequate pain relief for colostomy closure as part of a multimodal pain control.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

TRIPLE

Enrollment

Conditions

Postoperative Pain

Interventions

levo-bupivacaineDRUG

normal salineDRUG

Eligibility

Sex: ALLMin age: 20 YearsMax age: 75 Years

Medical Language ↔ Plain English

Inclusion Criteria: * A physical status between ASA I and III * 20 - 75 years of age * Patient has signed an informed consent * Without contraindication of QL block Exclusion Criteria * American Society of Anesthesiologists (ASA) Physical Status ≥ 4 * Any contraindication to nerve blocks (including coagulopathy, abnormal anatomy, infection at the planned QL injection site, and amide-type local anesthetic allergy) pregnancy or breast-feeding * Severe obesity (body mass index≥ 35 kg/m2) * Patients with a history of significant neurological, psychiatric, neuromuscular, cardiovascular, pulmonary, renal or hepatic disease * Allergy to NSAIDs * Infection at the QL injection site * Patients with major psychosis or drug and alcohol abuse * Patient unable to comprehend or use the verbal rating pain scoring system or patient-controlled analgesia pump

Outcomes

Primary Outcomes

cumulative morphine consumption

Time frame: 1 hour

Data from ClinicalTrials.gov

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