Intussusception is one of the most frequent causes of acute bowel and second most common cause of acute abdominal pain in pediatric age .95 % of cases are idiopathic, the rest are either due to pathological lead point or post operative. Treatment of intussusception must start with medical resuscitation, then radiological or operative reduction of intussusception. Our surgery team has used hydrocortisone with the medical resuscitation to improve the success rate of pneumatic reduction and decrease the number of reduction trials.
Experimental group will be given single dose IV Hydrocortisone 10 mg/kg with Resuscitation before attempting first trial of pneumatic reduction and the outcome measured. Control group will be given Saline 100 ml IV single injection with Resuscitation before attempting first trial of pneumatic reduction and the outcome measured.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
QUADRUPLE
Enrollment
80
10 mg/kg with Resuscitation before attempting pneumatic reduction, single dose with Resuscitation before attempting reduction
100 ml with Resuscitation before attempting pneumatic reduction, single dose with Resuscitation before attempting reduction
Cairo University Pediatric Hospital
Cairo, Egypt
RECRUITINGSuccess of Pneumatic Reduction
Comparing number of Successful Pneumatic Reductions in both groups
Time frame: 1 Hour
Reducing number of trials of Pneumatic Reduction
Comparing average number of Pneumatic Reduction trials between both groups
Time frame: 2 Hours
Reducing complications
Comparing number of complications in both groups
Time frame: 2 Hours
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