Hyaluronic Matrix Efficacy for Maxillary Sinus Augmentation

Hacettepe University13 enrolled

Overview

Sinus augmentation is a predictable method when alveolar bone height is not sufficient for dental implant placement in posterior maxillary alveolar region..The aim of this prospective, randomized, controlled clinical study is comparison of hyaluronic acid originated matrix and equine derived xenograft with only xenograft use in sinus augmentation by micro computed tomography and histomorphometry.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

NONE

Enrollment

Conditions

Sinus; Dental

Interventions

Maxillary Sinus AugmentationPROCEDURE

Each 0.5 cc Collagenated Heterolog Bone Graft, mixed with two bundles of Hyalossᵀᴹ matrix and a few drops of sterile saline solution

Maxillary Sinus AugmentationPROCEDURE

Control group sinuses filled with heterolog bone graft alone

Eligibility

Sex: ALLMin age: 33 YearsMax age: 69 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * Systemically healthy patients * Requiring bilateral maxillary sinus augmentation (residual crest height ≤ 4 mm) Exclusion Criteria: * Advanced systemic diseases * Chronic medication use * Maxillary sinus disease * Current pregnancy * Lactation * Smoking habit

Outcomes

Primary Outcomes

Percentage of newly formed bone calculated from bone biopsises by Micro-CT and Histomorphometry

Biological parameter obtained by analyzing bone biopsises

Time frame: 4 months after surgery

Data from ClinicalTrials.gov

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