A Phase III Clinical Trial of a Haemophilus Influenzae Type b (Hib) Conjugate Vaccine

Inclusion Criteria: * Healthy children aged 3-5 months/ 6-11 months/ 1-5 y for each age group * Without vaccination history of Hib conjugate vaccine * One of his/her guardians is able to understand and sign the informed consent * Subjects' guardian can and will comply with the requirements of the protocol * Subjects with temperature \<=37.0°C on axillary setting Exclusion Criteria: * Subject who has a medical or family history of any of the following: allergic history, seizure, epilepsy, brain or mental disease * Subject who is allergic to any ingredient of the vaccines * Subject with damaged or low immune function which has already been known * Subject who had a Hib disease medical history * Subject with acute febrile illness or infectious disease * Major congenital defects, developmental disorders or serious chronic illness * Thrombocytopenia, blood coagulation disorder or bleeding difficulties with intramuscular injection * Subject who has serious allergic history * Subject with other medical history not suitable for vaccination such as difficulty for blood collection * Any prior administration of immunodepressant or corticosteroids in last 6 months * Any prior administration of blood products in last 3 months * Any prior administration of other research medicine/vaccine in last 30 days * Any prior administration of any attenuated live vaccine in last 14 days * Any prior administration of subunit or inactivated vaccines in last 7 days, such as pneumococcal vaccine * Any medical, psychological, social or other condition judged by investigator, that may interfere subject's compliance with the protocol or his/her guardian's signature on informed consent