The purpose of the study is to assess the efficiency and safety of prophylactic use of antibiotics in endoscopic injection of tissue adhesive in gastric varices.
At present, there is still a controversy about the application of antibiotics in the treatment of patients with non acute hemorrhage of esophageal varices. This study is a randomized controlled trial. Patients randomly enter two treatment groups: 1. the prophylactic use of antibiotics group and 2. the non-prophylactic use of antibiotics group Treatment allocation is by block randomization with an equal number for both groups. The incidence of infection after endoscopic treatment will be analyzed.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
NONE
Enrollment
120
Prophylactic use of antibiotics group: Half an hour before endoscopic treatment, cefotiam 2.0g intravenous
Shanghai Zhongshan Hospital
Shanghai, Shanghai Municipality, China
RECRUITINGThe incidence of infection after endoscopic treatment
Patients will receive body temperature, blood routine, inflammatory markers examination before and after endoscopic treatment.
Time frame: 1 week
Rebleeding rate
Patients will receive an endoscopic examination after patients have been followed up for 2 months.
Time frame: 2 months
Mortality rate
The investigators observe the mortality events during 2 months
Time frame: 2 months
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.