The Effect of Obesity on Endometrium in PCOS

Assiut University100 enrolled

Overview

The effect of Polycystic Ovary Syndrome (PCOS) with or without obesity has received a few attentions. There is a lack of evidence to whether the BMI affects the endometrial blood flow, which is necessary for implantation.

Study Type

OBSERVATIONAL

Enrollment

100

Conditions

Body Weight Polycystic Ovary Syndrome

Interventions

Doppler evaluationDEVICE

Endometrial volume, endometrial and subendometrial vascularity indices are measured by 3D power Doppler

Eligibility

Sex: FEMALEMin age: 18 YearsMax age: 40 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Women with PCOS are diagnosed according to Rotterdam criteria, (Rotterdam and ASRM-Sponsored, 2004)by the presence of two out of the following three: oligomenorrhea (absence of menses for 35-182 days) or amenorrhea (absence of menses for \>182 days), signs or symptoms of hyperandrogenism (acne, hirsutism), US showing polycystic ovaries. * Fertile women had regular menstruation, with at least one previous spontaneous pregnancy. Exclusion Criteria: * Women known to have hepatic or renal dysfunction, Diabetes mellitus, hypertension, or cardiovascular disease. * If they have used induction of ovulation drugs for the last three months. * If they have used hormonal contraception in the last three months.

Locations (1)

Ahmed Abbas

Assiut, Cairo Governorate, Egypt

Outcomes

Primary Outcomes

the mean difference in Doppler indices (VI-FI-VFI)

Time frame: 24 hours

Data from ClinicalTrials.gov

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