Etodolac-lidocaine Patch in Subjects Experiencing Acute Delayed Onset Muscle Soreness

Inclusion Criteria: * Have not engaged in significant upper extremity fitness activities for more than two times per week for ≥ 2 consecutive weeks in the past 6 months prior to screening. * Subject has a body mass index of between 18 and 30 kg/m2, inclusive. * Subjects who report a pain with movement score in both arms of at least 5 (based on a 0-10 NRS) secondary to DOMS approximately 24 to 30 hours after each arm was exercised. Exclusion Criteria: * Presence of another painful physical condition that, in the opinion of the Investigator, may confound study assessments. * Use of pain medication (including anti-inflammatory drugs) prior to the Exercise Visit until 72 hours after randomization. * Use of any corticosteroids (oral, injectable, topical, inhaled) from before the Exercise Visit until randomization. Corticosteroids must be washed out by at least 3 days before the Exercise Visit. * Chronic or acute renal or hepatic disorder, inflammatory bowel disease (e.g., Crohn's disease or ulcerative colitis) or a significant coagulation defect. * History of allergy (cutaneous or systemic), asthma, hypersensitivity to any of the following: etodolac, lidocaine, paracetamol (acetaminophen), acetylsalicylic acid, salicylic acid, other NSAID, other local anesthetic, known intolerance (cutaneous or systemic) to any of the ingredients in the patch.