Addressing Psychosocial Comorbidities in HIV Treatment and Prevention

University of Miami27 enrolled

Overview

Project AProaCH is an open pilot trial of a cognitive behavioral therapy (CBT) for individuals with HIV with various psychological comorbidities, which the investigators call "syndemics". Syndemics are co-occurring psychosocial problems that interact with each other and with health behavior such as HIV sexual transmission risk behavior and adherence to self care.

Study Type

INTERVENTIONAL

Allocation

Purpose

TREATMENT

Masking

NONE

Enrollment

Conditions

Human Immunodeficiency Virus Depression Mental Health

Interventions

Cognitive Behavioral TherapyBEHAVIORAL

Integrating CBT for mental health and substance issues concern with CBT for health behavior change

Eligibility

Sex: ALLMin age: 18 YearsMax age: 65 Years

Medical Language ↔ Plain English

Inclusion Criteria: * HIV+ individuals * Uncontrolled virus (plasma HIV RNA concentrations that reach detectable limits) or being diagnosed with a sexually transmitted infection (STI) (gonorrhea, chlamydia, syphilis, trichomoniasis (female only)) currently or within the past 3 months. Exclusion Criteria: * Unable or unwilling to provide informed consent * Active untreated, unstable, major mental illness (i.e., untreated psychosis or mania) that would interfere with study participation * Opinion of the PI that the participant would be at risk for harm to himself or others as a result of study participation, * Under the age of 18 or over the age of 65, * Current CBT for a psychiatric disorder, or a course of CBT in the past year.

Locations (1)

University of Miami

Miami, Florida, United States

Outcomes

Primary Outcomes

Responder status as defined by the number of participants who change from a detectable to suppressed (undetectable) HIV viral load

Attaining viral suppression

Time frame: 4 months assessment

Responder status as defined by the number of participants who change from a detectable to suppressed (undetectable) HIV viral load

Attaining viral suppression

Time frame: 8 month assessment

Secondary Outcomes

Adherence to antiretroviral therapy via real time monitoring

Adherence to ART will be measured using a real time monitoring devices that tracks when a pill box is opened and closed.

Time frame: Changes over time from baseline to 8 month follow-up

Data from ClinicalTrials.gov

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