NCT02697695 - Chronic Inflammation After Obesity Surgery | Crick | Crick

Chronic Inflammation After Obesity Surgery

N/ACompletedNCT02697695

Sana Klinikum Offenbach500 enrolled

Overview

To evaluate the impact of obesity surgery on chronic inflammation.

A retrospective study to compare the impact of laparoscopic sleeve gastrectomy (LSG), laparoscopic Roux-en Y- gastric bypass (LRYGB) and laparoscopic omega-loop gastric bypass (LOLGB) on chronic inflammation and metabolic syndrome.

Study Type

OBSERVATIONAL

Enrollment

500

Conditions

Interventions

Laboratory ExaminationOTHER

Laboratory Examination before, 1 month, 3 month, 6 month and up to 12 month after LSK, LRNYGB, LOLGB

Eligibility

Sex: ALLMin age: 18 YearsMax age: 65 Years

Medical Language ↔ Plain English

Inclusion Criteria: * BMI \> 35kg/m² and obesity-related disease or BMI \> 40kg/m² Exclusion Criteria: * acute inflammation during laboratory examination

Outcomes

Primary Outcomes

Chronic inflammation

the changing of leucocytes in /nl after obesity surgery

Time frame: one day preoperatively, and 1 month, 3 month, 6 month and up to 12 month postoperatively

Secondary Outcomes

Fatty liver index

the changing of fatty liver index after obesity surgery

Time frame: one day preoperatively and 1 month, 3 month, 6 month and up to 12 month postoperatively

Liver enzymes

the changing of GOT in U/l, GPT in U/l, GGT in U/l, AP in U/l after obesity surgery

Time frame: one day preoperatively and 1 month, 3 month, 6 month and up to 12 month postoperatively

Body Mass Index (BMI) in kg/m²

the changing of BMI in kg/m² before and after obesity surgery

Time frame: one day preoperatively and 1 month, 3 month, 6 month and up to 12 month postoperatively

weight in kg

the changing of weight before and after obesity surgery

Time frame: one day preoperatively and 1 month, 3 month, 6 month and up to 12 month postoperatively

waist circumference

the changing of waist circumference in cm before and after obesity surgery

Time frame: one day preoperatively and 1 month, 3 month, 6 month and up to 12 month postoperatively

HbA1c

the changing of HbA1c in % and after obesity surgery

Time frame: one day preoperatively and 1 month, 3 month, 6 month and up to 12 month postoperatively

Data from ClinicalTrials.gov

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