Safety Study of Filler Agent Composed of Umbilical Cord Mesenchymal Stem Cells and Hyaluronic Acid

Inclusion Criteria: 1. Male or female over 18 years; 2. Have ability to understand and comply with the study requirements, and provide the written informed consent prior to any procedures ; 3. Suitable for the medical history and physical examination like the following preoperative laboratory tests results: complete blood count, coagulation, biochemistry, electrocardiogram, hepatogram and β-human chorionic gonadotropin (hCG) for women of childbearing age. Exclusion Criteria: 1. Patients unable to undergo surgery liposuction with Klein technique as those with severe cardiovascular disease, severe coagulation disorders including thrombophilia and pregnancy; 2. Have history or active dermal diseases, inflammation, or any related disease; 3. Had invasive aesthetic treatments or surgeries history 6 months before the treatments; 4. Had physical or chemical aesthetic treatments 1 months before the study starts; 5. Have a known history of allergic reactions like hypersensitivity to hyaluronic acid; 6. Patients with limited understanding of the procedure or have poor compliance with the study or follow-up schedule; 7. Pregnant or lactating; 8. Use of drugs; 9. Patients with preoperative results considered inadequate.