Ventricular Arrhythmias After Pulmonary Vein Isolation

Universitätsklinikum Hamburg-Eppendorf111 enrolled

Overview

The investigators study aimed to observe the occurrence of new premature ventricular complexes and other ventricular arrhythmias after pulmonary vein isolation.

Atrial fibrillation is the most common arrhythmia with a lifetime risk for development of over 20%. Pulmonary vein isolation is now established as therapy of choice for patients with symptomatic atrial fibrillation. It is well known that this interventional therapy inevitably modulates the intracardiac autonomic nervous system. While this ablation might alter atrial electrophysiology beneficially, the impact on ventricular electrophysiology remains unclear.

Study Type

OBSERVATIONAL

Enrollment

111

Conditions

Ventricular Arrhythmias Atrial Fibrillation

Eligibility

Sex: ALLMin age: 18 YearsMax age: 80 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Age \> 18 years * Paroxysmal atrial fibrillation scheduled to undergo pulmonary vein isolation Exclusion Criteria: * Age \< 18 years * Persistent atrial fibrillation * Life expectancy less than 12 months * Acute myocardial infarction, coronary artery bypass graft surgery, open heart surgery, or percutaneous transluminal coronary angioplasty within less than 3 months prior to inclusion * Documentation of \>30 premature ventricular complexes per hour, salvos or ventricular tachycardias prior to atrial fibrillation ablation

Locations (1)

Department of Cardiology - Electrophysiology, University Heart Centre, University Hospital Hamburg-Eppendorf

Hamburg, Germany

Outcomes

Primary Outcomes

Ventricular arrhythmias

Number of patients with premature ventricular complexes, ventricular tachycardias or ventricular fibrillation.

Time frame: one year

Secondary Outcomes

Arrhythmia recurrence

Number of patients with premature ventricular complexes, ventricular tachycardias or ventricular fibrillation.

Time frame: one year

Data from ClinicalTrials.gov

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