This study aims at evaluating the effect of adding magnesium sulphate epidurally as an adjunct to levobupivacaine on the quality of anesthesia and perioperative pain relief in patients with preeclampsia undergoing elective caesarian section (CS).
Pregnant women with preeclampsia undergoing elective CS in will be included in the study. All patients participating in the study will be randomly divided into two groups; magnesium sulphate group (study group) and placebo group (control group). Patients in the study group will receive epidural 20 ml levobupivacaine hydrochloride 0.5% plus 5 ml magnesium sulphate 10% (500 mg) while patients in the control group will received epidural 20 ml levobupivacaine hydrochloride 0.5% plus 5 ml saline 0.9%.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
SUPPORTIVE_CARE
Masking
QUADRUPLE
Enrollment
60
Patients will receive epidural 20 ml levobupivacaine hydrochloride 0.5%
Patients will receive epidural 5 ml magnesium sulphate 10%
Patients will receive epidural 5 ml saline 0.9%
Mansoura University Hospital
Al Mansurah, Dakahlia Governorate, Egypt
Pain-free period
The time from reaching sensory block to onset of pain
Time frame: 24 hours after the epidural anesthesia
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