Endoscopic Evaluation After Esophagectomy

Nagasaki University10 enrolled

Overview

Gastric conduit ischemia or anastomotic breakdown after esophagectomy with cervical esophagogastrostomy often cause severe complications, such as leakage, necrotic organs, and strictures. Thus, the purpose of this study is the safety and efficacy of endoscopic evaluation about reconstructive organs after esophagectomy. The investigators evaluate endoscopic predictions using classifications in acute phase after esophagogastrostomy.

Gastric conduit ischemia or anastomotic breakdown after esophagectomy with cervical esophagogastrostomy often cause severe complications, such as leakage, necrotic organs, and strictures. However the evaluation and prevention before developing gastric conduit ischemia have been established. The investigators have built a hypothesis that the evaluation for gastric mucosal ischemia in early phase after esophagectomy predict the complication of gastric conduit. Thus, the purpose of this study is the safety and efficacy of endoscopic evaluation about reconstructive organs after esophagectomy. The investigators evaluate endoscopic predictions using classifications in acute phase after esophagogastrostomy.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Esophageal Neoplasms Constriction Anastomotic Leak Ischemia

Interventions

Patients after esophagectomyPROCEDURE

postoperative endoscopic evaluation

Eligibility

Sex: ALLMin age: 20 YearsMax age: 84 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Malignant or end-stage benign esophageal disease. * Esophagectomy with reconstruction by a gastric pull-up. Exclusion Criteria: * Severe heart failure and pulmonary dysfunction * Severe renal and liver dysfunction * Allergenic history * Pregnancy

Locations (1)

Nagasaki University Hospital

Nagasaki, Nagasaki, Japan

Outcomes

Primary Outcomes

Number of participants with endoscopy-related adverse events as assessed by Clavien-Dindo Classification