The objective of this study is to detect the effect of trans-cranial direct current stimulation on postoperative pain and opioid consumption in total knee arthro-plasty patients. Fifty patients undergoing unilateral TKA will be randomly assigned to receive 4 sessions, total of 80 minutes of real (n=25) or sham tDCS (n=25). Stimulation will be given on 4 consecutive postoperative days, group 1 will receive real stimulation with the active electrode over the leg representation of the motor strip (cortical motor area of the leg) and the reference electrode over the arm, group 2 will receive Sham tDCS. Pain level will be evaluated according to visual analogue scale (VAS) and LANSS pain scale before (base line) after 1st, 2nd, 3rd and 4th sessions.
The study aims to to detect the effect of trans-cranial direct current stimulation on postoperative pain and opioid consumption in total knee arthro-plasty patients. Fifty patients undergoing unilateral TKA will be randomly assigned to receive 4 sessions, total of 80 minutes of real (n=25) or sham tDCS (n=25). Stimulation will be given on 4 consecutive postoperative days, group 1 will receive real stimulation with the active electrode over the leg representation of the motor strip (cortical motor area of the leg) and the reference electrode over the arm, group 2 will receive Sham tDCS. Pain level will be evaluated according to visual analogue scale (VAS) and LANSS pain scale before (baseline) after 1st, 2nd, 3rd and 4th sessions.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Enrollment
46
Opioids consumption per 24 hours at the 4th day postoperative
Measuring the consumption dose of opioids per 24 hours at the fourth day
Time frame: day 4 postoperative
Opioids consumption / 24 hours at the third day postoperative
Measuring the consumption dose of opioids per 24 hours at the third day postoperative
Time frame: day 3 postoperative
Opioids Consumption / 24 hours at the second day postoperative
Measuring the consumption dose of opioids per 24 hours at the second day post-operative
Time frame: day 2 postoperative
Opioids consumption / 24 hours at the 1st day postoperative
Measuring the consumption dose of opioids per 24 hours at the 1st day postoperative
Time frame: 1st day postoperative
Opioid side effects
Record Opioid-related adverse effects (nausea and/or vomiting and the need for alizapride 50mg IV).
Time frame: 4th post operative day
Pain assessment by VAS
Pain Assessment using Visual Analogue Scale
Time frame: 3rd postoperative day
Pain assessment by VAS
Pain Assessment using Visual Analogue Scale
Time frame: 2nd postoperative day
Pain assessment by VAS
Pain Assessment using Visual Analogue Scale
Time frame: 1st postoperative days
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