Study of Bacteroides Thetaiotaomicron in Young People Aged 16 to 18 Years With Stable Crohn's Disease

Inclusion Criteria: 1. Subjects aged 16 to 18 years inclusive, with confirmed diagnosis of Crohn's disease who are currently in clinical remission\* in the opinion of the investigator and who are otherwise healthy. 2. Subjects who are able and willing to give written informed consent to participate. If applicable, a parent/carer may also give consent to their participation. Exclusion Criteria: 1. Subjects who are pregnant or breastfeeding. 2. Subject who are experiencing an exacerbation at the time of screening or up to the time of the first dose. 3. Subjects who have undergone previous surgery for resection of bowel. 4. Subjects who have fistulisation. 5. Subjects who have had a significant change in their immune-modulating maintenance medication in the 3 months prior to screening and/or the start of dosing. 6. Subjects who have taken systemic steroids in the last 3 months. 7. Subjects who are unable to take any oral feeding. 8. Subjects with feeding gastrostomies. 9. Subjects who have non-food dietary supplementation for any reason changed within 1 month prior to dosing. 10. Subjects who have received monoclonal antibodies in the 6 months prior to dosing. 11. Subjects who have received antibiotics or probiotic dietary supplementation in the two weeks before dosing. Subjects who have received foods with probiotics e.g. yoghurts will be permitted to volunteer for the study. 12. Subjects who are receiving exclusive enteral feeding or have completed a course of exclusive enteral feeding in the 3 months prior to dosing. 13. Subjects with concomitant autoimmune diseases. 14. Female Subjects of child bearing potential unwilling to use effective contraception from the signing of the consent form until completion of two periods after the last dose. An effective method of birth control is defined as one which results in a low failure rate (i.e. less than 1% per year) when used consistently and correctly such as sterilisation, implants, injectables, combined oral contraceptives, Intrauterine Device (IUD), condoms, occlusive caps (cervical/vault caps) with spermicidal foam/gel/film/cream/pessary. True sexual abstinence is acceptable when this is in line with the preferred and usual lifestyle of the subject. 15. Subjects with clinically significantly, in the opinion of the investigator, elevated platelets, white cell count, C-reactive protein, erythrocyte sedimentation rate (ESR), low albumin or haemoglobin. 16. Subjects who are positive for the following viruses: HIV, hepatitis B and hepatitis C. 17. Subjects who smoke cigarettes or use other tobacco or nicotine containing products, including e-cigarettes. 18. Subjects who have a known sensitivity to any of the constituents of the investigational medicinal compound. 19. Diastolic blood pressure \<50 or \>90 mmHg, a systolic blood pressure \<100 or \>150 mmHg, a pulse \<40 or \>100 beats per minute (bpm) after resting for 5 minutes. 20. Subjects with clinically significantly abnormal ECGs or structural cardiac abnormalities e.g. valvular heart disease, patent foramen ovale. 21. BMI Z SCORE less than -2.6 or greater than 2.6 (0 ± 2.6); i.e. below the 2nd centile or greater than the 98th centile. 22. Any condition that, in the opinion of the Investigator, might interfere with the primary study objective. 23. Subjects allergic to metronidazole and co-amoxiclav