Identify, by Lipidomics approaches, biochemical markers of fertility / infertility in sperm and seminal plasma linking the success or failure of the artificial insemination (IUI)
Analyze lipid profiles in samples of sperm and seminal plasma of three populations: 1. male sperm donors 2. men assigned to a program of assisted reproduction with normal sperm / slightly abnormal successfully in the IUI; 3. attached to a program of assisted reproduction with male semen Normal / slightly abnormal unsuccessfully in IUI Establish partnerships between the composition of fatty acids, especially fatty acids polyunsaturated (PUFA) of the omega-3 (w3) series of samples analyzed parameterssemen and results of the IA to identify biochemical markers of fertility. Assess markers found by checking the increase in the rate of success in the IA.
Study Type
OBSERVATIONAL
IVI Bilbao
Leioa, Vizcaya, Spain
Identify, by Lipidomics approaches, biochemical markers of fertility / infertility sperm and seminal plasma linking the success or failure of the artificial insemination
Levels of docosahexaenoic acid (DHA) and acid eicosapentaenoic (EPA) in 42 semen samples: * With positive pregnancy in any of the first 4 treatments of artificial insemination. * Gestacion Negative in artificial insemination * Assigned to the program-donors donation
Time frame: 18 months
Descriptive analysis of semen parameters versus DHA and EPA levels
Correlation analysis of seminal variables: sperm count, motility and morphology percent compared to the levels of DHA and EPA obtained. Assuming normal distribution continuous variables, ANOVA test apply. If the normality assumption failed an Kruskal-Wallis test was applied.
Time frame: 18 months
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