Effect of EPA-DHA Supplement, Life Style Modification Standard Treatment on Clinical Outcome Lipid Membrane Composition in Type 2 Diabetes

Inclusion Criteria: 1. Participants between 18-80 years of age. 2. Have been diagnosed with type 2 diabetes more than nine months before study entry, and, despite having been given standard dietary advice by dietitian, doctor, or nurse and prescribed oral hypoglycaemic agents, insulin, or both. 3. Have persistent unsatisfactory glycaemic control defined as HbA1c more than 7%. 4. Participants should have at least two of the following three characteristics: 1. Overweight or obesity (body mass index ≥25), 2. Hypertension (currently prescribed antihypertensive drugs or blood pressure \>140/90 mm Hg despite optimized antihypertensive drug treatment), 3. Dyslipidaemia (currently prescribed lipid modifying drugs) or one or more of: <!-- --> 1. total cholesterol \>5.2 mmol/l, 2. low density lipoprotein cholesterol \>3.5 mmol/l, 3. triglycerides \>2.0 mmol/l, 4. high density lipoprotein cholesterol \<1.0 mmol/l (despite optimised lipid modifying drug treatment). Exclusion Criteria: 1. Pregnancy 2. Serious chronic illness.e.g cancer 3. End stage renal failure 4. Amputation 5. Stroke 6. Severe retinal microangiopathy 7. Pancreas transplantation 8. HbA1c \<7% 9. Requires diet only treatment 10. They are too busy with work