Patients visiting National Hospital of Odonto-Stomatology for treating periodontitis used a food supplement (lozenge) containing chicken egg antibody (IgY) against Porphyromonas gingivalis gingipains as an adjunct to conventional scaling and root planing (SRP). After 8 weeks the patients were examined against. Parameters including probing depth (PD), bleeding on probing (BOP), number of P. gingivalis in periodontal pockets were evaluated and compared to the control group that had used placebo lozenges.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
SUPPORTIVE_CARE
Masking
DOUBLE
Enrollment
60
Patients consumed food supplement lozenges containing IgY after nonsurgical periodontal therapy
Placebo IgY
Effect of anti-gingipain IgY on probing pocket depth of subjects with chronic periodontitis
Outcome measurement is probing pocket depth (PD)
Time frame: 8 weeks
Effect of anti-gingipain IgY on bleeding on probing of subjects with chronic periodontitis
Outcome measurement is bleeding on probing (BOP)
Time frame: 8 weeks
Effect of anti-gingipain IgY on Porphyromonas gingivalis level of subjects with chronic periodontitis
Outcome measurement is P. gingivalis level in periodontal pockets
Time frame: 8 weeks
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