TeleRehabilitation in Hypertension

KU Leuven60 enrolled

Overview

The purpose of this RCT which will be performed in 60 healthy adults is I. To assess the training effects of 8 weeks of isometric handgrip exercise on BP; and to test whether it yields at least similar effects on BP compared to current exercise recommendations. II. To assess whether isometric handgrip training yields larger BP reductions beyond the supervised training period at 6 months of follow-up. III. To determine whether changes in BP following acute exercise and chronic training can be explained by changes in important physiological mechanisms known to mediate or to be associated with BP?

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

SINGLE

Enrollment

Conditions

Hypertension Pre-hypertension Healthy

Interventions

Isometric handgrip exerciseOTHER

Participants have to perform 4 x 2 minute contractions with alternating hands, separated with 1 minute rest period using a ZonaHealth device;

Aerobic endurance trainingOTHER

To perform 150 minutes extra/week at moderate aerobic intensity

Eligibility

Sex: ALLMin age: 18 YearsMax age: 65 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * not physically active (\< 3 hours of moderate to high levels of PA/week) low cardiovascular risk according to current guidelines (Mancia et al J Hypertens 2013) will be recruited through advertisements. The latter is defined as: * \>115 mmHg \< systolic BP \< 139 mmHg and/or 75 mmHg\< diastolic BP\<90mmHg in the presence of 0 to a maximum of three other cardiovascular risk factors, excluding diabetes Or * 139 mmHg \< systolic BP \< 160 mmHg and/or 90 mmHg\<DBP\< 100 mmHg in the absence of other cardiovascular risk factors Exclusion Criteria: * current smoker * pregnancy * presence of other cardiovascular disease, pulmonary disease or metabolic disease * inability to perform a standard exercise program due to mental/physical disability. * use of antihypertensive drugs

Locations (1)

KU Leuven

Leuven, Belgium

Outcomes

Primary Outcomes

change in office blood pressure at 8 weeks of follow-up

Time frame: 8 weeks - 6 months

Secondary Outcomes

change in exercise tolerance (peakVO2 in ml/min/kg) at 8 weeks of follow-up

Time frame: 8 weeks - 6 months

Data from ClinicalTrials.gov

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