Oxygenation with high-flow nasal cannula with 100% oxygen has only been evaluated in a limited number of studies. Although data are convincing it is of importance to evaluate this new concept in our department before implementing it into clinical practice. The general purpose of this project is to evaluate a new ventilation strategy during ENT-surgery based on oxygenation with high-flow nasal cannula with 100% oxygen with focus on gas exchange.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
31
Change in arterial carbon dioxide (pCO2)
Time frame: From start of anaesthesia to end of apnoea oxygenation or max 30 minutes
Change in arterial pH
Time frame: From start of anaesthesia to end of apnoea oxygenation or max 30 minutes
Change in arterial oxygen tension (pO2)
Time frame: From start of anaesthesia to end of apnoea oxygenation or max 30 minutes
Does hyperventilation prior to anaesthesia and apnoea oxygenation cause any difference in pCO2 in the end of the apnea (i.e. at up to 30 minutes) compared to normoventilation?
Time frame: In the end of the apnoea period, i.e. at approximately 20 minutes
Does hyperventilation prior to anaesthesia and apnoea oxygenation cause any difference in pH in the end of the apnea (i.e. at up to 30 minutes) compared to normoventilation?
Time frame: In the end of the apnoea period, i.e. at approximately 20 minutes
Does hyperventilation prior to anaesthesia and apnoea oxygenation cause any difference in pO2 in the end of the apnea (i.e. at up to 30 minutes) compared to normoventilation?
Time frame: In the end of the apnoea period, i.e. at approximately 20 minutes
Does the high oxygen content cause atelectasis measures as change in relation between pCO2 and end tidal carbon dioxide
Time frame: Until discharge from the postoperative unit, often max 2 hours
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