Paracetamol Versus Placebo in Conjunction With Strong Opioids for Cancer Pain

Inclusion Criteria: 1. Age 16 years and over 2. Under palliative care/oncology service review 3. Diagnosis of incurable cancer 4. Clinician-predicted life expectancy \>2 months 5. Anticipated to be clinically stable for duration of study involvement 6. Receiving daily regular strong opioids 7. Able to take study drug/placebo in its current form 8. Prescribed and taking paracetamol 1g four times a day 9. Average pain \>3 and \<9 in past 24 hours 10. Able to provide written informed consent 11. Able to complete necessary assessments required as part of the trial 12. Average NRS pain score stable (ie. maximum range of 1 point) for the three consecutive days prior to randomisation Exclusion Criteria: 1. Pain which the clinician deems to be unstable 2. Clinically significant renal or liver disease 3. Weight less than 50kg 4. Those whose pain is expected to change during the course of the study as a result of oncological or other treatments 5. Co-enrolment in other drug trials 6. Known to be pregnant or breast-feeding at the time of recruitment 7. Previously enrolled in this study