The goal of this project is to evaluate the influence of platelet rich fibrin (PRF) in extraction socket healing with or without particulate bone graft. The hypothesis of this study is that PRF will enhance the extraction socket healing and new bone formation when compared to extraction sockets grafted without PRF.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
42
Extraction with socket grafting using PRF.
Extraction with socket grafting using bone graft.
The University of Texas Health Science Center at Houston School of Dentistry
Houston, Texas, United States
Change in alveolar ridge width (buccal-lingual)
Baseline is at the time of extraction with or without socket grafting.
Time frame: baseline, 3 months
Change in alveolar ridge height (apical coronal)
Baseline is at the time of extraction with or without socket grafting.
Time frame: baseline, 3 months
Percentage of vital bone in bone core as assessed histology
A bone core will be taken at 3 months after socket grafting.
Time frame: 3 months
Percentage of residual bone graft in bone core as assessed histology
A bone core will be taken at 3 months after socket grafting.
Time frame: 3 months
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