Fluid management of children during neurosurgery is not well established. Hypotonic solutions, commonly still used in pediatric patients, may enhance cerebral edema and worse operative conditions. This study compares two different isotonic solutions administered perioperatively regarding acid base and fluid electrolyte disturbances.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Enrollment
53
Federal University of Sao Paulo
São Paulo, São Paulo, Brazil
serum chloride difference (mmol/L)
Serum chloride will be collected in two different moments: right before the beginning of the surgery and right after de end of the procedure. We will calculate the difference between the two values.
Time frame: from the admission of the patient in the operating room until the end of the surgery.
serum chloride difference (mmol/L)
Serum chloride will be collected right after the end of the surgery as well as 24 hours after the admission in ICU. We will calculate the difference between the two values.
Time frame: from the end of the surgery until exactly 24 hours after the admission in intensive care unit (ICU)
brain relaxation score
Time frame: immediately after dura-mater opening
serum sodium difference (mmol/L)
Serum sodium will be collected in two different moments: right before the beginning of the surgery and right after de end of the procedure. We will calculate the difference between the two values.
Time frame: from the admission of the patient in the operating room until the end of the surgery.
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