Glyceryl Trinitrate Versus Lidocaine Cream for IUD Insertion

Assiut University150 enrolled

Overview

The intrauterine device (IUD) is a long-acting, highly effective, reversible contraceptive method that may be underutilized due to fear of pain during insertion. Although providers frequently prescribe non-steroidal anti-inflammatory drugs (NSAIDs) for IUD insertion, there is no evidence for any pain reduction. Women can experience high levels of pain when the IUD is placed inside the uterus, and fear of this pain could be a reason that women decide not to use this method.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

TRIPLE

Enrollment

150

Conditions

IUD Insertion

Interventions

glyceryl trinitrate creamDRUG

lidocaine creamDRUG

placebo creamDRUG

Eligibility

Sex: FEMALEMin age: 18 YearsMax age: 49 Years

Medical Language ↔ Plain English

Inclusion criteria: 1. Women not taken analgesics or anxiolytics in the 24 hours prior insertion 2. Women not taken misoprostol prior to IUD insertion 3. No contraindication to or history of allergic reaction to lidocaine or NO donors. 4. Women who will accept to participate in the study Exclusion criteria: 1. Lidocaine allergy 2. History of migraine or chronic headache 3. Any contraindication to IUD placement

Locations (1)

Ahmed Abbas

Assiut, Cairo Governorate, Egypt

Outcomes

Primary Outcomes

Mean pain score during IUD insertion

Time frame: 3 minutes

Secondary Outcomes

Patient satisfaction score after the procedure

Time frame: 3 minutes

Data from ClinicalTrials.gov

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