Four Methods of Pre-oxygenation

Hennepin Healthcare Research Institute26 enrolled

Overview

Four methods of preoxygenation will be compared in healthy volunteers

After informed consent, each volunteer will undergo the following techniques: Simple mask at "flush" flow (40-60 L/min) Non-rebreather mask at 15 L/min Non-rebreather mask at 60 L/min Bag valve mask with one way exhalation valve at 15 L/min After 3 minutes, the exhaled oxygen will be measured with an oxygen sensor

Study Type

INTERVENTIONAL

Allocation

NON_RANDOMIZED

Purpose

TREATMENT

Masking

NONE

Enrollment

Conditions

Respiratory Failure

Interventions

PreoxygenationDEVICE

After 3 minutes of oxygen supplementation (preoxygenation), with each of the devices listed below, the exhaled oxygen content will be measured. All participants were enrolled in a single arm in which they underwent 4 interventions in series: 1) Simple mask at 60 L/min for 3 minutes 2) Non-rebreather at 60 L/min for 3 min 3) Non-rebreather at 15 L/min for 3 minutes 4) Bag valve mask at 15 L/min for 3 minutes

Eligibility

Sex: ALLMin age: 18 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * Over 18 years old Exclusion Criteria: * Any active respiratory pathology (asthma, chronic obstructive pulmonary disease, other lung disease, smoking history more than 5 years) * pregnant

Outcomes

Primary Outcomes

Exhaled Oxygen Concentration

Subjects will blow into an oxygen sensor after each method (arm). The primary outcome will be a non-inferiority test between bag valve mask and non-rebreather at 60 L/min. The remaining tests will be completed for comparison, but not part of formal statistical testing.

Time frame: Immediately after 3 minutes of oxygen supplementation

Data from ClinicalTrials.gov

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