Continuous Infusion for Pain Relief

Tunisian Military Hospital60 enrolled

Overview

SPINAL anesthesia is commonly used for cesarean section, and it has become a popular practice to add opioids to spinal solutions to enhance and prolong intraoperative and postoperative analgesia. high incidence of side effects was noted. is there any alternative?

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

QUADRUPLE

Enrollment

Conditions

Regional Anesthesia Caeserian Section Local Anesthetic

Interventions

control groupDRUG

spinal anesthesia with 10 mg hyperbaric Bupivacaïne 0,5% + 2,5 µ Sufentanyl + 100 µ of intrathecal Morphine+ infiltration catheter with saline 5 ml/h

infiltration groupDRUG

spinal anesthesia with 10 mg hyperbaric Bupivacaïne 0,5% + 2,5 µ Sufentanyl + 1ml of saline + infiltration catheter with 5 ml/h of Bupivacaïne 0,125%.

Eligibility

Sex: FEMALEMin age: 18 YearsMax age: 45 Years

Medical Language ↔ Plain English

Inclusion Criteria: * ASA physical status I-II * 18-45 years of age, inclusive * elective caeserean section under spinal anesthesia Exclusion Criteria: * \- contraindications to spinal anesthesia (e.g., allergy to local anesthetics, coagulopathy, malignancy or infection in the area) * existing neurological deficit * inability to understand the informed consent and demands of the study

Outcomes

Primary Outcomes

Visual Analogic Scale

quality of postoperative analgesia

Time frame: until 48 hours postoperative

Secondary Outcomes

occurrence of complications

Time frame: 48 hours post operative

total dose of morphine consumption in mg

Time frame: during 48 hours post operative

Data from ClinicalTrials.gov

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