The main objective will be to evaluate the effect at 5 weeks of nutritional management associated with protein supplementation (adapted to the post-operative period) on the maintenance of lean body mass at the whole body in obese patients after a sleeve gastrectomy. Secondary objectives will assess protein intake, food safety, the effect of protein supplementation on body fat in the entire body and the metabolic rate and the impact on quality of life and post-operative joint pain.
The main objective will be to evaluate the effect at 5 weeks of nutritional management associated with protein supplementation (adapted to the post-operative period) on the maintenance of lean body mass at the whole body in obese patients after a sleeve gastrectomy. Secondary objectives will assess protein intake, food safety, the effect of protein supplementation on body fat in the entire body and the metabolic rate and the impact on quality of life and post-operative joint pain. There is still no study evaluating the protein supplementation adapted patients after sleeve gastrectomy on maintaining lean body mass.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
NONE
Enrollment
90
Protein supplementation : Protein intake of 30 grams of protein in addition to the usual inputs (to the recommended amounts of 60 to 120 g per day), upon the resumption of oral intake until the fifth week after sleeve gastrectomy.
UHMontpellier
Montpellier, France, France
Changes in lean mass (kg) will be assessed at the level of whole-body dual-energy X-ray absorptiometry (DXA)
Time frame: up to 1 month
food diary
The actual protein intake will be assessed using a food diary over 5 weeks completed by the patient
Time frame: 5 weeks after the hospital discharge
change rate IGF1, IGFBP3
change rate IGF1, IGFBP3 between hospitalization and 1 month of hospital discharge
Time frame: up to 1 month
the quality of life
The evolution of the quality of life will be assessed through a specific scale, Baros score.
Time frame: up to 1 month
the quality of life
The evolution of the quality of life will be assessed through a specific scale, Baros score.
Time frame: up to 5 years
change rate IGF1, IGFBP3
change rate IGF1, IGFBP3 between hospitalization and 5 years follow up
Time frame: up to 5 years
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.