This study estimates the treatment goal achievement rate, depicts the implementation of the Progressive Psoriasis Initiative (PPI) recommendations regarding treatment modifications and transitioning, and assesses patient adherence and persistence with adalimumab therapy in the routine clinical practice in Greece.
Study Type
OBSERVATIONAL
Enrollment
273
Proportion of participants who will achieve the European Consensus Programme (ECP)-defined treatment goals at the end of the induction phase (i.e. 16 weeks post-treatment onset)
Achievement of the treatment goals during the induction phase is defined as: * Treatment Success: i.e. \>=75% Psoriasis Area Severity Index (PASI) score reduction OR * Intermediate Response with Dermatology Life Quality Index (DLQI) \<=5: i.e. PASI score reduction \>=50% but \<75% with DLQI \<=5.
Time frame: 16 weeks post-treatment
Proportion of participants achieving intermediate response
Intermediate response is defined as participants with PASI score reduction \>=50% but \<75% compared to week 0 (baseline).
Time frame: Up to 12 months
Proportion of participant achieving treatment success
Treatment success rate is defined as participants with \>=75% PASI score reduction compared to week 0 (baseline).
Time frame: Up to 12 months
Proportion of participant with treatment failure
Treatment failure is defined as participants with PASI score reduction \<50% compared to week 0 (baseline).
Time frame: Up to 12 months
Proportion of participants achieving the treatment goals
According to the European Consensus Programme (ECP) guidelines, achievement of the treatment goals during the maintenance phase is defined as: * Treatment Success: i.e. \>=75% Psoriasis Area Severity Index (PASI) score reduction compared to the time of therapy initiation (i.e. baseline) (or) * Intermediate Response with Dermatology Life Quality Index (DLQI) \<=5: i.e. PASI score reduction \>=50% but \<75% compared to baseline, with DLQI \<=5.
Time frame: Up to 12 months
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.
General Univ Hosp "Attikon" /ID# 149517
Athens, Attica, Greece
Tzaneio general hospital of Piraeus /ID# 149518
Piraeus, Attica, Greece
General Uni hosp of Larissa /ID# 149688
Larissa, Thessaly, Greece
General Uni hosp of Larissa /ID# 151442
Larissa, Thessaly, Greece
PP of Konstantinos Tsaousis /ID# 149704
Amaliáda, Greece
PP of Maria Sifaki /ID# 149717
Arkalochóri, Greece
General Hospital of Athens Evaggelismos and Ophthalmiatrio of Athens Polyclinic /ID# 158934
Athens, Greece
PP of Michael Kakepis /ID# 149693
Athens, Greece
PP of Georgios Papadopoulos /ID# 149712
Athens, Greece
PP of Ioannis Krikellis /ID# 149715
Athens, Greece
...and 33 more locations
Time to the first missed dose during the study observation period
Patient diary will be reviewed to assess this information
Time frame: Up to 12 months