The Impact of Salpingectomy and Single Dose Systemic Methotrexate Treatments on Ovarian Reserve in Ectopic Pregnancy

Ege University131 enrolled

Overview

The investigators aimed to investigate the effects of salpingectomy and Methotrexate administration on ovarian reserve in ectopic pregnancy.

In this study, the effects of unilateral laparoscopic salpingectomy and single dose of systemic Methotrexate administration on ovarian reserve in patients diagnosed with ectopic pregnancy were investigated.

Study Type

INTERVENTIONAL

Allocation

NON_RANDOMIZED

Purpose

TREATMENT

Masking

NONE

Enrollment

131

Conditions

Ectopic Pregnancy Infertility

Interventions

MethotrexateDRUG

single dose systemic methotrexate administration (50 mg/m2)

salpingectomyPROCEDURE

Laparoscopic unilateral salpingectomy

Eligibility

Sex: FEMALEMin age: 18 YearsMax age: 45 Years

Medical Language ↔ Plain English

Inclusion Criteria: * ectopic pregnancy diagnosis Exclusion Criteria: * history of endometriosis, ovarian surgery, systemic chemotherapy, ART treatment. * patients treated with multiple doses of methotrexate or different surgical procedure (salpingostomy, milking)

Locations (1)

Ege University School of Medicine Department of Obstetrics and Gynecology

Izmir, Turkey (Türkiye)

Outcomes

Primary Outcomes

Ovarian reserve assessment by measuring AMH level.

Ovarian reserve were assessed before and after treatment by measuring AMH levels.

Time frame: 1-3 months

Secondary Outcomes

Number of participants with treatment related adverse effect on fertility.

Rates of term delivery, spontaneous abortion, recurrent ectopic pregnancy and ongoing pregnancy for each group of patients were calculated during 2 years of follow up period.

Time frame: 2 years of follow up after treatment

Data from ClinicalTrials.gov

This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.