Serum Zinc, Peptic Ulcer Disease and H. Pylori Infection

Ain Shams University75 enrolled

Overview

Fifty consecutive patients with symptoms suggestive of peptic ulcer disease were included. All underwent complete clinical evaluation, laboratory investigations, upper gastrointestinal endoscopy and rapid urease test. Measurement of serum zinc level was done for all the included patients in addition to twenty five age and sex matched healthy control subjects.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Peptic Ulcer Disease

Interventions

Upper gastrointestinal endoscopyPROCEDURE

Thorough examination of the esophagus, stomach and duodenum to the second part was done to all patients using Olympus CV-150 or Pentax EPM-3500.

Eligibility

Sex: ALLMin age: 18 YearsMax age: 55 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Symptoms suggestive of peptic ulcer disease like epigastric pain, dyspepsia, heartburn Exclusion Criteria: * Patients who received zinc supplementation, proton pump inhibitors (PPI), non-steroidal anti-inflammatory drugs (NSAIDs) * Those presented with hematemesis or melena * Those with chronic liver disease, renal failure, malabsorption or previous gastric surgery

Outcomes

Primary Outcomes

Detection of positive upper GIT endoscopic findings

Time frame: upon endoscopy

Data from ClinicalTrials.gov

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