In the current study, the investigators plan to expand the knowledge of Positron Emission Tomography/Magnetic Resonance (PET/MR) reliability by assessing the repeatability of fludeoxyglucose (FDG) standardized uptake values (SUV) measurements, as well as apparent diffusion coefficients (ADC) measurements, in a broad population of patients with malignant solid tumors.
Study Type
INTERVENTIONAL
Allocation
NA
Purpose
DIAGNOSTIC
Masking
NONE
Enrollment
19
Washington University School of Medicine
St Louis, Missouri, United States
Variability of repeated quantitative measures of FDG uptake as measured by SUVmax
-SUVmax is the maximum standardized uptake value (SUV) of the area of showing metabolic activity and this is used to show response
Time frame: Completion of study (up to Day 7)
Variability of repeated quantitative measures of FDG uptake as measured by SUVpeak
-SUVpeak, which is defined as the average SUV within a 1 cubic cm volume within the region of the tumor with the highest metabolic activity
Time frame: Completion of study (up to Day 7)
Repeatability of diffusion-weighted imaging on PET/MR as measured by difference in mean ADC
* DW MRI is a method of mapping the diffusion process of water within and between tissues * Water diffusion is described quantitatively by apparent diffusion coefficients (ADC)
Time frame: Completion of study (up to Day 7)
Repeatability of diffusion-weighted imaging on PET/MR as measured by differences in minimum ADC
* DW MRI is a method of mapping the diffusion process of water within and between tissues * Water diffusion is described quantitatively by apparent diffusion coefficients (ADC)
Time frame: Completion of study (up to Day 7)
Evaluation of the ratio of SUVmax and ADCmin
Time frame: Completion of study (up to Day 7)
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