This is a multi-center prospective observational study that will capture detailed information about the treatment and long term outcomes of 250 patients with PNI resulting from upper extremity trauma. The study will focus on a young adult population to include individuals ages 18-65. Patients with PNI will be recruited during the hospitalization for initial treatment of the upper extremity injury. Additional patients may be identified during clinic visits for on-going treatment of upper extremity injuries as nerve injuries evolve or upon referral from outside physicians. However, all eligible nerve injuries must be treated within 6 months of the initial upper extremity trauma. Outcomes will be assessed at 3, 6, 12, 18 and 24 months following diagnosis of the nerve injury. All assessments will take place in the clinic and will include a patient interview and a brief exam to evaluate sensory and motor function.
Study Type
OBSERVATIONAL
Enrollment
242
Denver Health
Denver, Colorado, United States
Ryder Trauma Center
Miami, Florida, United States
Methodist Hospital
Bloomington, Indiana, United States
University of Maryland Medical Center Shock Trauma Center
Baltimore, Maryland, United States
The Curtis National Hand Center, Medstar Union Memorial Hospital
Baltimore, Maryland, United States
Walter Reed National Military Medical Center
Bethesda, Maryland, United States
Hennepin County Medical Center
Minneapolis, Minnesota, United States
University of New Mexico Health Sciences Center
Albuquerque, New Mexico, United States
Carolinas Medical Center
Charlotte, North Carolina, United States
Wake Forest Baptist Health
Winston-Salem, North Carolina, United States
...and 7 more locations
Incidence of Peripheral Nerve Injury (PNI) resulting from upper extremity trauma admitted across multiple trauma centers.
Time frame: 2 years
Type of PNI resulting from upper extremity trauma admitted across multiple trauma centers.
Time frame: 2 years
Treatment type of PNI resulting from upper extremity trauma admitted across multiple trauma centers.
Time frame: 2 years
Treatment timing of PNI resulting from upper extremity trauma admitted across multiple trauma centers.
Time frame: 2 years
Surgical Complications
Surgical complications includes surgical site infections, wound dehiscence/breakdown, exposure of nerves and/or their repairs and reconstructions, breakdown of nerve repair and reconstruction, seroma/hematoma, and other local wound complications.
Time frame: 2 years
Pain Score
Self reported outcomes using the Brief Pain Inventory.
Time frame: 2 years
Sensory Function
Sensory function will be evaluated using the the touch test mono-filament hand evaluation kit.
Time frame: 2 years
Motor Function
Motor function will be evaluated using range of motion and the British Medical Research Council motor grading scale.
Time frame: 2 years
Global Hand Function
Global hand function will be measured using grip strength.
Time frame: 2 years
Disability
Self reported outcomes using the Disabilities of the Arm, Shoulder and Hand questionnaire (DASH).
Time frame: 2 years
Depression
Self reported outcomes using the Patient Health Questionnaire (PHQ-9).
Time frame: 2 years
Post Traumatic Stress Disorder (PTSD)
Self reported outcomes using the standard PTSD Checklist.
Time frame: 2 years
Return to Work or Duty
Self reported outcomes using the Work Productivity and Activity Impairment (WPAI) questionnaire.
Time frame: 2 years
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