MC5-A Scrambler Therapy or TENS Therapy in Treating Patients With Chemotherapy-Induced Peripheral Neuropathy

Inclusion Criteria: * Pain or symptoms of CIPN of \>= 3 months duration, for which the patient wants intervention * Note: neurotoxic chemotherapy must have been completed \>= 3 months prior to registration and there must be no further planned neurotoxic chemotherapy for \> 5 months after registration * Patients have to relate that tingling or pain was at least a four out of ten problem =\< 7 days prior to registration, on a 0-10 scale where zero was no problem and ten was the worst possible problem * Note: the patient is expected to have tingling or pain of at least 4/10 at the time of the first treatment * Eastern Cooperative Oncology Group (ECOG) performance status (PS) = 0, 1, or 2 * Life expectancy \>= 6 months * Ability to complete questionnaire(s) by themselves or with assistance * Ability to provide informed written consent * Case review by the study chair, or designate, as a case where treatment should be tried Exclusion Criteria: * Any of the following: * Pregnant women * Nursing women * Women of childbearing potential who are unwilling to employ adequate contraception * Existing operational implantable drug delivery systems, e.g. Medtronic Synchromed * Existing implantable medical electronic devices, life-supporting medical devices, and medical monitoring devices * Note: metal implants for orthopedic repair, e.g. pins, clips, plates, cages, joint replacements are allowed as are central venous access devices * History of myocardial infarction or ischemic heart disease within the past six months * History of epilepsy, brain damage, use of anticonvulsants for seizure prevention, concurrently using ketamine, symptomatic brain metastases * Skin conditions such as open sores that would prevent proper application of the electrodes * Other medical or other condition(s) that in the opinion of the investigators might compromise the objectives of the study * Currently receiving gabapentin or pregabalin and not willing to be weaned off of these medications prior to Scrambler therapy initiation * Note: it is OK to continue these medications in patients who are receiving TENS * History of peripheral neuropathy prior to receiving neurotoxic chemotherapy * Prior treatment with Scrambler therapy