In this observational study patients with subarachnoid hemorrhage (SAH) will be screened for sleep apnea (SA) to investigate if SA is associated with impaired blood pressure control and worse clinical outcome early after SAH.
Patients admitted with non-traumatic SAH will be consented and screened for sleep apnea within 48 hours after hospital admission. Blood pressure and clinical outcome will be monitored throughout ICU treatment and hospital stay, respectively. Diagnosis of sleep apnea will be confirmed on follow-up 3-6 month after SAH by sleep apnea screening (portable cardiorespiratory monitoring and out-of-center polysomnography, respectively).
Study Type
OBSERVATIONAL
Enrollment
200
Department of Neurology and Department of Neurosurgery
Bonn, Germany
RECRUITINGTime to blood pressure target
The time required to reach blood pressure target as defined by care provider.
Time frame: Within 10 Days of hospital admission with subarachnoid hemorrhage
Medication needed to achieve blood pressure target
Blood pressure medication required to reach blood pressure target as defined by care provider.
Time frame: Within 10 Days of hospital admission with subarachnoid hemorrhage
Change in modified ranking scale (mRS) from baseline to discharge and follow-up visit, respectively.
Change in modified ranking scale at hospital discharge and at follow-up (3-6 month after SAH) will be assessed and compared between patients with and without sleep apnea. The change from baseline to discharge/follow-up will be compared between groups.
Time frame: 3 to 6 Month after SAH
Change in NIH stroke scale score (NIHSS) from admission to discharge and follow-up visit, respectively.
Neurological outcome measured as score in NIHSS at hospital discharge and at follow-up (3-6 month after SAH) will be assessed and compared between patients with and without sleep apnea. The change from baseline to discharge/follow-up will be compared between groups.
Time frame: 3 to 6 Month after SAH
Barthel Index at discharge at follow-up visit, respectively.
Impairment of daily living (score in Barthel index) at discharge and at follow-up visit (3 to 6 month after SAH) will be assessed. The change from baseline to discharge/follow-up will be compared between groups.
Time frame: 3 to 6 Month after SAH
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