Study to Evaluate Safety and Efficacy of Dapagliflozin in Patients With Type 2 Diabetes Mellitus Aged 10-24 Years

Inclusion Criteria 1. Provision of informed consent prior to any study-specific procedures 2. Males and Females, ages 10 years of age, up to but not including 25 years of age at the time of randomization 3. Previously diagnosed as having type 2 diabetes for at least 2 months by WHO/ADA diagnostic criteria 4. HbA1c \>= 6.5% and \<= 11% obtained at screening visit 5. Currently on diet and exercise and a stable dose of metformin (at least 1000 mg daily) for a minimum of 8 weeks, or stable dose of insulin for a minimum of 8 weeks, or a stable combination of metformin (at least 1000 mg daily) and insulin for a minimum of 8 weeks prior to screening 6. FPG \<=255 mg/dL (\<= 14.2 mmol/L) obtained at screening visit Exclusion Criteria: 1. Previous diagnosis of Type 1 diabetes 2. Diabetes ketoacidosis (DKA) within 6 months of screening 3. Current use of the following medications for the treatment of diabetes, or use within the specified timeframe prior to screening for the main study: * Eight weeks: sulfonylureas, alpha glucosidase inhibitors, metiglinide, or injectable incretins or incretin mimetics or other antidiabetes medications not otherwise specified * Sixteen weeks: thiazolidinediones * Any previous history or current use of an SGLT2 inhibitor, including dapagliflozin 4. Initiation or discontinuation of prescription or non-prescription weight loss drugs within 8 weeks of screening. Use of prescription or non-prescription weight loss drugs must be stable during the study 5. Pregnant, positive serum pregnancy test, planning to become pregnant during the clinical trials, or breastfeeding 6. History of unstable or rapidly progressive renal disease 7. History of unresolved vesico-ureteral reflux 8. Replacement or chronic systemic corticosteroid therapy, defined as any dose of systemic corticosteroid taken for \> 4 weeks within 3 months prior to the Day 1 visit. Note: Topical, nasal, or inhaled corticosteroids are allowed 9. Abnormal renal function, which is defined in subjects \< 18 years of age as an estimated glomerular filtration rate (eGFR) calculated by the Schwartz Formula \< 80 mL/min/1.73 m2 (1.33 mL/s), and in subjects \>= 18 years as an estimated glomerular filtration rate (eGFR) calculated by the MDRD Formula \< 60 mL/min/1.73 m2 (1.33 mL/s) 10. Presence of either: antibodies to glutamic acid decarboxylase (GAD) or protein tyrosine phosphatase-like protein antibodies (IA-2) 11. An abnormal TSH value at screening will be further evaluated for free T4. Subjects with abnormal free T4 values will be excluded 12. Hematuria (confirmed by microscopy at screening) with no explanation as judged by the investigator up to randomization 13. Anemia of any etiology defined as hemoglobin \<=10.7 g/dL (107 g/L) for females and \<= 11.3 g/dL (113 g/L) for males. Subjects who are considered to have anemia according to local guidelines should be excluded 14. Volume-depleted subjects. Subjects at risk for volume depletion due to co-existing conditions or concomitant medications, such as loop diuretics, should carefully monitor their volume status