this study investigates the analgesic efficacy and other possible effects of ketamine, morphine, and both together when administered intrathecally for control of postoperative pain following lower abdominal cancer surgeries.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
TRIPLE
Enrollment
90
patients received 10 mg of hyperbaric bupivacaine 0.5% in 2 ml volume and 0.3 mg intrathecal morphine1 ml volume.
patients received 10 mg of hyperbaric bupivacaine 0.5% in 2 ml volume and 0.1 mg/kg intrathecal ketamine in 1ml volume.
patients received 10 mg of hyperbaric bupivacaine 0.5% in 2 ml volume and intrathecal morphine + ketamine 0.3 mg and 0.1 mg/kg respectively in 1 ml volume.
Visual Analogue Scale (VAS) scores
postoperative pain measured by this score.
Time frame: 24 hours postoperative
time to first analgesic request
the time passed till the first request of rescue analgesia by the patients
Time frame: 24 hours postoperative
total analgesic consumption
the total amount of rescue analgesic drug used allover follow up period
Time frame: 24 hours postoperative
side effects
the type and rate of incidence of side effects during the follow up period
Time frame: 24 hours postoperative
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