The IBSEN III study will investigate the incidence of inflammatory bowel disease in South Eastern Norway and describe the clinical course of the disease. The investigators will map newly diagnosed and treatment naive IBD patients at various levels (epidemiological, clinical, psychosocial and nutritional as well as immunological, genetic, epigenetic and microbial) as a basis to improve targeted and individualized treatment and care. The investigators will include incident IBD patients at all local- and university hospitals in the South Eastern Health Region in 2016-2018 and follow-up prospectively for five years. The investigators will use standardized and validated registration methods allowing comparability with previous national and international IBD cohorts, link data to national health registries and collect blood, feces and biopsies for bio banking.
Study Type
OBSERVATIONAL
Enrollment
2,286
Oslo University Hospital
Oslo, Norway
Evidence for ulcerative colitis, Crohn's disease or indeterminate colitis based on specific clinical, endoscopic, histological and radiological criteria
Diagnosis according to the Lennard Jones Criteria for the diagnosis of inflammatory bowel disease
Time frame: At baseline
Change in IBD diagnosis between baseline and one year follow-up
Change in diagnosis based on specified clinical, endoscopic, histological and radiological criteria
Time frame: 1 year (+/-3 months)
Change in IBD diagnosis between one year and five year follow-up
Change in diagnosis based on specified clinical, endoscopic, histological and radiological criteria
Time frame: 5 year (+/-3 months)
Change in disease classification (montreal Classification) between baseline and one year follow-up.
Change in disease extension and severity as defined in the Montreal classification system for IBD
Time frame: 1 year (+/-3 months)
Change in disease classification (montreal Classification) between one and five year follow-up
Change in disease extension and severity as defined in the Montreal classification system for IBD
Time frame: 5 year (+/-3 months)
IBD related bowel surgery
Bowel surgery for any IBD related condition
Time frame: 1 year (+/-3 months)
IBD related bowel surgery
Bowel surgery for any IBD related condition
Time frame: 5 year (+/-3 months)
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