Preoperative Ketorolac for Pain Control in Scleral Buckle Surgery

Sun Yat-sen University73 enrolled

Overview

The scleral buckle surgery is an effective way in treating retinal detachment (RD) patients. Retrobulbar block has been proved effective in scleral buckle surgery. Though retrobulbar anesthesia saves operative time and money compared to general analgesia, the intraoperative pain is frequent and a proportion of postoperative pain is often ignored. Ketorolac has been demonstrated to be a preemptive analgesia in other diseases such as adenotonsillectomy, posterior lumbar spinal fusion, laser-assisted subepithelial keratectomy (LASEK), and so forth. The aim of the investigators study is to determine the safety and preemptive analgesic effect of ketorolac in the perioperative pain control of patients undergoing RD surgery under retrobulbar anesthesia.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

SUPPORTIVE_CARE

Masking

QUADRUPLE

Enrollment

Conditions

Pain

Interventions

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: 1. consent of the patient or legal guardian 2. 18 years or above 3. normal height and weight 4. ASA class I, II 5. elective surgery 6. surgery time within 60min 7. understanding of the verbal numerical rating score (0-10) Exclusion Criteria: 1. history of ocular surgery, trauma or infection 2. intraoperative complications 3. glaucoma or ocular hypertension (\> 20 mmHg) 4. diabetic retinopathy 5. diagnosis of asthma or coagulopathy 6. chronic pain syndromes 7. history of peptic ulceration, liver or hematologic disease 8. history of chronic use of analgesics, sedatives, opioids or steroids 9. history of drug or alcohol abuse 10. history of systemic disease 11. sexually transmitted disease (STD) 12. Pregnancy, lactation; 13. cognitive impairment or psychiatric illness;