Gene Polymorphism of Taste Receptors and Circulating Endocannabinoids in Normal Weight and Obese Subjects

University of Cagliari110 enrolled

Overview

The study aims at evaluating in normal weight and obese subjects those factors such as taste sensitivity and circulating endocannabinoids in influencing dietary choice and thereby lipid and energy metabolism in order to design personalized nutritional strategies.

Study Type

OBSERVATIONAL

Enrollment

110

Conditions

Nutritional Physiological Phenomena

Eligibility

Sex: ALLMin age: 20 YearsMax age: 70 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * Body Mass Index (BMI), range for normal weight subjects 17.5-24.95, for obese subjects 29.6-52.20 * No intake of nutritional supplements for at least six months before the trial Exclusion Criteria: * major diseases (diabetes, kidney disease, etc.), * pregnancy or lactation; * food allergies; * the use of medications that interfere with taste or smell (e.g., steroids, antihistamines, certain antidepressants).

Outcomes

Primary Outcomes

Endocannabinoid plasma levels

Time frame: 1 year

Data from ClinicalTrials.gov

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