The Pharmacokinetics, Safety, and Ease of Use of a Portable Metered-Dose Cannabis Inhaler

Inclusion Criteria: * aged 30-70 years; * healthy * if applicable, negative pregnancy test (β human chorionic gonadotropin pregnancy test). Exclusion Criteria: * significant cardiac or pulmonary disease, * history of a psychotic or anxiety disorder, * pregnancy, pregnancy attempt or breastfeeding, * presence of a neuropathic or non-neuropathic pain, * low blood pressure, below 90 mm Hg (systolic) * Diabetes is diagnosed, * first degree family history of psychotic or anxiety disorder, * history of drug addiction, * history of drug misuse, * using the following drugs: Rifampicin, Rifabutin, Carbamazepine, Phenobarbital, Primidone, * using the following plants: Hypericum perforatum, troglitazone, * Alcohol consumption up to 12 hours before the study, * abnormal parameters such as Heart Rate above 100 BPM, Blood pressure, below 90 mm Hg (systolic), Saturation below 91 percent, * Cannabis use up to 12 hours before the study, * health condition which could affect or alter the experiment results, * Volunteer has a legal guardian. * Chronic use of drugs, * age less than 30 or more than 70, * a health condition that could affect the outcome of the trial or constitutes a risk factor for participation in the trial. * The experiment will not include special populations such as pregnant women, children and without judgement.