This is an observational, "ancillary study" intended to describe opioid use among opioid use disorder patients following their discharge into the community from inpatient detoxification and/or short-term residential treatment programs affiliated with parent study CTN-0051, which assessed the comparative effectiveness of extended release injectable naltrexone (XR-NTX, Vivitrol®), an opioid antagonist recently approved and indicated for the prevention of relapse to opioid dependence, versus buprenorphine-naloxone (BUP-NX, Suboxone®), a high affinity partial agonist indicated for maintenance treatment of opioid dependence, as pharmacotherapeutic aids to recovery.
Participant recruitment will begin after recruitment for CTN-0051 has been completed. Opioid use disorder patients will be recruited prior to leaving detoxification and/or short-term residential programs. Screening and baseline data (focused on demographics, diagnosis and service utilization) will be collected prior to discharge, and follow-up data (focused on opioid use) will be collected at weeks 1, 4 and 8 following discharge.
Study Type
OBSERVATIONAL
Enrollment
211
Tarzana Treatment Centers
Tarzana, California, United States
Gateway Community Services, Inc.
Jacksonville, Florida, United States
Stanley Street Treatment and Resources
Fall River, Massachusetts, United States
Bellevue Hospital
New York, New York, United States
Maryhaven
Columbus, Ohio, United States
Days of Opioid Use
Days of use during the first 4 weeks post discharge
Time frame: Up to Week 4 Post Discharge
Positive Urine Drug Screen (UDS) at Week 1
Number of positive UDSs at Week 1
Time frame: week 1
Negative UDSs at Week 1
Number of negative UDSs at Week 1
Time frame: week 1
Missing UDSs at Week 1
Number of missing UDSs at Week 1
Time frame: week 1
Missing UDSs at Week 4
Number of missing UDSs at Week 4
Time frame: week 4
Positive UDSs at Week 4
Number of positive UDSs at Week 4
Time frame: week 4
Negative UDSs at Week 4
Number of negative UDSs at Week 4
Time frame: week 4
Missing UDSs at Week 8
Number of missing UDSs at Week 8
Time frame: week 8
Negative UDSs at Week 8
Number of negative UDSs at Week 8
Time frame: week 8
Positive UDSs at Week 8
Number of positive UDSs at Week 8
Time frame: week 8
Time to First Use
Days to first opioid use from Timeline Followback
Time frame: Up to Week 8 Post Discharge
Time to Regular Use
Days to regular opioid use from Timeline Followback
Time frame: Up to Week 8 Post Discharge
Days of Opioid Use
Days of use up 8 weeks post discharge
Time frame: Up to Week 8 Post Discharge
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